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TODAY’S PATENT – PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES

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TODAY’S PATENT – PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES

The Prevention of disulfide bond reduction during recombinant production of polypeptides was invented by Yung-Hsiang KaoMichael W. LairdMelody Trexler SchmidtRita L. WongDaniel P. Hewitt on the 31st August, 2021, bearing patent number US11078294B2.

The invention concerns methods for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.

The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.

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    Ishita Goyal

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