TODAY’S PATENT – PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES

The Prevention of disulfide bond reduction during recombinant production of polypeptides was invented by Yung-Hsiang KaoMichael W. LairdMelody Trexler SchmidtRita L. WongDaniel P. Hewitt on the 31^st August, 2021, bearing patent number US11078294B2.

The invention concerns methods for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.

The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.